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《医学前沿(英文)》 2017年 第11卷 第2期 页码 266-276 doi: 10.1007/s11684-017-0530-y
Childhood obesity and obesity-related metabolic complications are induced by a high-fat postnatal diet. The lack of a suitable animal model, however, remains a considerable challenge in obesity studies. In the current study, we provided high-fat diet (HFD) to dams during lactation and to pups after weaning. We also developed a novel model of C57BL/6J mouse pups with HFD-induced postnatal obesity. Results showed that feeding with HFD induces fat deposition and obesity in pups. Furthermore, HFD more potently increased the body weight (BW) of male than female pups. HFD-fed female pups were obese, underwent precocious puberty, and showed increased kisspeptin expression in the hypothalamus. However, parental obesity and precocious puberty exerted no synergistic effects on the HFD-induced postnatal weight gain and puberty onset of the pups. Interestingly, some HFD-fed litters with normal BW also exhibited precocious puberty. This finding suggested that diet composition but not BW triggers puberty onset. Our model suggests good construction validity of obesity and precocious puberty. Furthermore, our model can also be used to explore the mutual interactions between diet–induced postnatal childhood obesity and puberty.
关键词: postnatal HFD feeding obesity kisspeptin HPG axis precocious puberty
Anion-exchange membrane direct ethanol fuel cells: Status and perspective
T.S. Zhao, Y.S. Li, S.Y. Shen
《能源前沿(英文)》 2010年 第4卷 第4期 页码 443-458 doi: 10.1007/s11708-010-0127-5
关键词: fuel cell direct ethanol fuel cells anion-exchange membrane ethanol oxidation reaction oxygen reduction reaction cell performance
Astrocytes in depression and Alzheimer’s disease
《医学前沿(英文)》 2021年 第15卷 第6期 页码 829-841 doi: 10.1007/s11684-021-0875-0
关键词: astrocytes depression Alzheimer’s disease roles mechanisms
基于马尔可夫到达过程的两级可修备件(S-1,S)库存优化模型
陈 童,黎 放,狄 鹏
《中国工程科学》 2015年 第17卷 第5期 页码 113-119
《环境科学与工程前沿(英文)》 2022年 第16卷 第1期 页码 14-14 doi: 10.1007/s11783-022-1538-3
Exergy analysis and simulation of a 30MW cogeneration cycle
Nikhil Dev, Samsher, S. S. Kachhwaha, Rajesh Attri
《机械工程前沿(英文)》 2013年 第8卷 第2期 页码 169-180 doi: 10.1007/s11465-013-0263-9
Cogeneration cycle is an efficient mean to recover the waste heat from the flue gases coming out of gas turbine. With the help of computer simulation, design parameters may be selected for the best performance of cogeneration cycle. In the present work a program is executed in software EES on the basis of mathematical modelling described in paper to study cogeneration cycle performance for different parameters. Results obtained are compared with the results available in literature and are found in good agreement with them. Real gas and water properties are inbuilt in the software. Results show that enthalpy of air entering the combustion chamber is higher than that of the flue gases at combustion chamber outlet. For different operative conditions, energy and exergy efficiencies follow similar trends; although, exergy efficiency values are always lower than the corresponding energy efficiency ones. From the results it is found that turbine outlet temperature (TIT) of 524°C is uniquely suited to efficient cogeneration cycle because it enables the transfer of heat from exhaust gas to the steam cycle to take place over a minimal temperature difference. This temperature range results in the maximum thermodynamic availability while operating with highest temperature and highest efficiency cogeneration cycle. Effect of cycle pressure ratio (CR), inlet air temperature (IAT) and water pressure at heat recovery steam generator (HRSG) inlet on the 30 MW cogeneration cycle is also studied.
关键词: Cogeneration cycle air compressor HRSG gas turbine regenerator CR IAT
Development of environmental management system in China's financial sector
CHANG Miao, PENG Lijuan, WANG Shiwen
《环境科学与工程前沿(英文)》 2008年 第2卷 第2期 页码 172-177 doi: 10.1007/s11783-008-0032-x
标题 作者 时间 类型 操作
Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups: a
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期刊论文
Society for Neuroscience's 49th Annualmeeting
2019年10月19日
会议信息
RTS,S/AS01疟疾疫苗(英文)
2024年01月16日
会议视频
Anion-exchange membrane direct ethanol fuel cells: Status and perspective
T.S. Zhao, Y.S. Li, S.Y. Shen
期刊论文
Exergy analysis and simulation of a 30MW cogeneration cycle
Nikhil Dev, Samsher, S. S. Kachhwaha, Rajesh Attri
期刊论文